APLYSINOPSIN


SMILES CN1C(=N)N(C)/C(=C/c2c[nH]c3ccccc23)C1=O
InChIKey AZGOVLGMSGAOMP-FZYUQVBKSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 254.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.06 5.06 5.06 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.35 5.35 5.35 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 4.84 4.92 5.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.22 6.22 6.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database