CHEMBL4062535


SMILES CC(C)Nc1ccc(-c2ccn3c(CC4CC4)nnc3c2Cl)cc1F
InChIKey CPRAFSBECNYZNT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 358.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.21 7.21 7.21 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKd 7.69 7.69 7.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 6.65 6.65 6.65 ChEMBL