CHEMBL4062602


SMILES O=C1COc2ccccc2N1CCCN1CCC(c2noc3cc(F)ccc23)CC1
InChIKey LSCKFBHTQUPRNT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 409.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.57 8.57 8.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.49 8.49 8.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MCH1 MCHR1 Human Melanin-concentrating hormone A pIC50 5.49 5.49 5.49 ChEMBL