CHEMBL4063837


SMILES CC(C)(C)C[C@@H]1COCc2nc(OCc3ccccn3)cc(=O)n21
InChIKey QDIYOEYPJWXMRN-CQSZACIVSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 329.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pKi 8.21 8.21 8.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.89 7.89 7.89 ChEMBL
μ OPRM Human Opioid A pEC50 5.0 5.0 5.0 ChEMBL