CHEMBL4064186


SMILES O=C1CCc2ccc(OCCCCN3CCN(c4ccc(O)c5ncccc45)CC3)cc2N1
InChIKey OYKQSDLPRQMVDA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 446.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.47 5.47 5.47 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.03 7.03 7.03 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.82 5.82 5.82 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.57 7.57 7.57 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.41 7.41 7.41 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.47 8.64 8.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database