CHEMBL112244


SMILES CN(CCCCCCN)CCCCCCCCN(C)CCCCCCNCC(=O)N1c2ccccc2C(=O)Nc2cccnc21
InChIKey CVYMNORESIPOLC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 24
Molecular weight (Da) 621.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Rat Acetylcholine (muscarinic) A pKi 7.8 7.8 7.8 ChEMBL
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 6.33 6.41 6.48 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 8.11 8.24 8.37 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 8.36 8.46 8.57 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 7.95 8.02 8.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database