CHEMBL4065797


SMILES CCCN1CCCN(c2ccc(O)c3c2OCC(=O)N3)CC1
InChIKey QLRIUZVNMLEJEJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 305.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.68 6.68 6.68 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.06 5.06 5.06 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.43 8.43 8.43 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.43 5.43 5.43 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.44 6.85 7.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 5.96 5.96 5.96 ChEMBL