CHEMBL123938


SMILES NNC(=O)[C@H]1CCCCNC(=O)CCC(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N1
InChIKey SVNSNKFQLBXSEH-ISSPZXTRSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 10
Rotatable bonds 9
Molecular weight (Da) 781.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pKi 6.27 6.27 6.27 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.82 6.82 6.82 ChEMBL
MC4 MC4R Human Melanocortin A pKi 9.3 9.3 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pEC50 6.28 6.28 6.28 ChEMBL