CHEMBL4078348


SMILES CCCN(CCCCOc1ccn2nccc2c1)[C@H]1CCc2c(O)cccc2C1
InChIKey IWAHIMCMPBOXKG-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 393.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.92 8.92 8.92 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.1 6.1 6.1 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.1 9.1 9.1 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.68 8.91 9.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 9.37 9.37 9.37 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.26 8.63 9.92 ChEMBL