CHEMBL423440


SMILES COc1ccc(Br)cc1C(=O)NC[C@H]1CCN(Cc2ccccc2)C1
InChIKey YBRBKCXISVCUJG-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 402.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.28 5.28 5.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.68 5.68 5.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.7 5.76 5.82 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.34 7.34 7.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database