CHEMBL425023


SMILES Cc1ccc(C#N)c(Nc2ccc3oc(CCN4CCC[C@H]4C)cc3c2)n1
InChIKey ZSLMOYVTOZQGFI-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 360.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.75 7.75 7.75 ChEMBL
H3 HRH3 Human Histamine A pKi 8.53 8.53 8.53 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database