CHEMBL4292719


SMILES O=C(NCc1ccccc1)C1CCN(C(=O)c2ccc(-c3ccccc3)cc2)CC1
InChIKey PLXQZCKNWRLVJF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 398.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.07 5.07 5.07 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.25 6.25 6.25 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.01 6.01 6.01 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.03 5.03 5.03 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.17 5.17 5.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database