CHEMBL4111574


SMILES O=C(Nc1ccc([C@@H]2CCCNC2)cc1)c1cnc(OCC(F)(F)F)cn1
InChIKey RYWVQJFDHSUWOD-CYBMUJFWSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 380.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Rat Trace amine A pKi 8.25 8.25 8.25 ChEMBL
TA1 TAAR1 Mouse Trace amine A pKi 6.54 6.54 6.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database