(R,S)-MEFLOQUINE


SMILES O[C@H](c1cc(C(F)(F)F)nc2c(C(F)(F)F)cccc12)[C@@H]1CCCCN1
InChIKey XEEQGYMUWCZPDN-SWLSCSKDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 378.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2B AA2BR Human Adenosine A pKi 5.15 5.15 5.15 ChEMBL
A3 AA3R Human Adenosine A pKi 5.16 5.16 5.16 ChEMBL
A2A AA2AR Human Adenosine A pKi 7.21 7.21 7.21 ChEMBL
A1 AA1R Human Adenosine A pKi 6.59 6.6 6.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database