CHEMBL432155


SMILES Cc1c(Nc2ncc[nH]2)ccc2c1NCCO2
InChIKey JDFLCCTUDMVCCS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 230.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Rat Adrenoceptors A pKi 6.38 6.38 6.38 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.64 6.64 6.64 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.22 8.22 8.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Rat Adrenoceptors A pEC50 6.33 6.33 6.33 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 6.96 6.96 6.96 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 6.91 6.91 6.91 ChEMBL