forasartan


SMILES CCCCc1nc(nn1Cc1ccc(nc1)c1ccccc1c1n[nH]nn1)CCCC
InChIKey YONOBYIBNBCDSJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 416.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Human Angiotensin A pKd 8.2 8.2 8.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Human Angiotensin A pIC50 8.16 8.16 8.16 ChEMBL
AT1 AGTRB Rat Angiotensin A pIC50 8.16 8.16 8.16 ChEMBL
AT1 AGTRB Rat Angiotensin A pIC50 8.2 8.4 8.6 Guide to Pharmacology