CHEMBL4115977


SMILES CCC(=O)NC1CN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)C1
InChIKey ICZVKTVMHVHOQI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 16
Molecular weight (Da) 949.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.11 7.11 7.11 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.44 8.44 8.44 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.7 6.7 6.7 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.15 9.15 9.15 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 8.08 8.31 8.52 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.15 8.15 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database