CHEMBL411663


SMILES O=C1Nc2ccc(F)cc2C1CCCCN1CCN(c2ccccc2)CC1
InChIKey IBBIDLLHDNJIPV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 367.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.33 7.35 7.36 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.7 7.7 7.7 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.81 6.81 6.82 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.72 5.72 5.72 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.26 7.26 7.26 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database