CHEMBL431041


SMILES CC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1
InChIKey VCYDEUCPMLCHGS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 272.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.6 6.6 6.6 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.21 6.21 6.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pEC50 7.44 7.44 7.44 ChEMBL