CHEMBL4161308


SMILES CC(C)c1nc2c(N3CCNCC3)ccnc2n1Cc1cccc(Cl)c1
InChIKey OQJMIPYHRMQITD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 369.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.15 5.15 5.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.16 6.16 6.16 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.64 5.64 5.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.53 5.53 5.53 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.25 7.25 7.25 ChEMBL