CHEMBL4167315


SMILES COc1cccc(-c2ccc3c(c2)CN(Cc2ccccc2)C3)c1
InChIKey LGSGJWDXMWVXEB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 315.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.06 6.06 6.06 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 5.84 5.84 5.84 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.04 6.04 6.04 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.77 5.77 5.77 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.41 6.41 6.41 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.59 5.59 5.59 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.7 5.7 5.7 ChEMBL
κ OPRK Human Opioid A pKi 5.5 5.5 5.5 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.54 5.54 5.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database