CHEMBL4176474


SMILES O=C(OCc1ccccc1)N1Cc2ccc(N3CCN(C4CCCC4)CC3)cc2C1
InChIKey FUWNTUBEOVLTGS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 405.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKi 5.79 5.79 5.79 ChEMBL
H2 HRH2 Human Histamine A pKi 5.97 5.97 5.97 ChEMBL
H1 HRH1 Human Histamine A pKi 6.23 6.23 6.23 ChEMBL
H3 HRH3 Human Histamine A pKi 6.78 6.78 6.78 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.67 5.67 5.67 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database