CHEMBL4440484


SMILES CCCC(C)(C)C(=O)N(CC)CCCC1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc32)CC1
InChIKey LOAZWNRCWBWKAC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 532.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.5 6.5 6.5 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.3 7.3 7.3 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.1 8.1 8.1 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.5 6.5 6.5 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.4 6.4 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database