CHEMBL116172


SMILES COc1ccccc1CNCCCCCCN(C)CCCCCCCCN(C)CCCCCCNCC(=O)N1c2ccccc2C(=O)Nc2cccnc21
InChIKey NEXSUYYCMZKEBX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 28
Molecular weight (Da) 741.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 6.1 6.1 6.1 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 8.77 8.77 8.77 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 7.55 7.55 7.55 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 8.51 8.51 8.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database