CHEMBL4214709


SMILES O=C1Nc2ccccc2C12CCN(CCN1CCN(c3ccc(Cl)c(Cl)c3)CC1)C2
InChIKey MOFMPCSTQOOMEP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 444.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.42 7.42 7.42 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.39 5.39 5.39 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database