CHEMBL4226226


SMILES CN(C)c1ccc(C(=O)NCCCCN2CCC(c3cccc(O)c3)C2)cc1
InChIKey UVSNDTNJIHHUPU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 381.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 6.02 6.26 6.51 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.87 7.07 7.27 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.34 5.71 6.08 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.57 7.76 7.87 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.48 6.75 6.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.44 6.45 6.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database