CHEMBL448155


SMILES COc1ccc([C@H](N)[C@@H]2CCN2C(c2ccccc2)c2ccccc2)cc1
InChIKey JNBBLYXYLWVZBN-GOTSBHOMSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 358.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 6.7 6.7 6.7 ChEMBL
δ OPRD Human Opioid A pKi 5.54 5.54 5.54 ChEMBL
κ OPRK Human Opioid A pKi 5.87 5.87 5.87 ChEMBL
μ OPRM Human Opioid A pKi 6.06 6.06 6.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database