CHEMBL423671


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(-c3ccc(S(C)(=O)=O)cc3)cc2)CC1
InChIKey CWADTSDGYTVLDK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 521.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 6.8 6.8 6.8 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.5 9.5 9.5 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.6 7.6 7.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database