CHEMBL4244280


SMILES O=S(=O)(c1cncc2ccccc12)N1CCCC[C@@H]1CCN1CCN(c2cccc3sccc23)CC1
InChIKey LWDHUYPVZPEUAM-HSZRJFAPSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 520.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.66 6.66 6.66 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.64 7.64 7.64 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.19 7.19 7.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database