CHEMBL425574


SMILES Cc1ccc(NC(=O)c2[nH]c(C3(C)CCCCC3)nc2CCC23CC4CC(CC(C4)C2)C3)cc1C(=O)O
InChIKey PZLNPXKYCTZVAW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 503.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Rat Cholecystokinin A pKd 9.05 9.05 9.05 ChEMBL
CCK2 GASR Mouse Cholecystokinin A pKi 8.48 8.48 8.48 ChEMBL
CCK1 CCKAR Guinea pig Cholecystokinin A pKi 6.6 6.6 6.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Dog Cholecystokinin A pIC50 7.95 7.95 7.95 ChEMBL