CHEMBL4514672
SMILES | CC1=NC2(CCN(C)CC2)C(=O)N(c2c(C)cccc2C)C1=O |
InChIKey | UOZGZTQNYJCRFH-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 0 |
Rotatable bonds | 1 |
Molecular weight (Da) | 313.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H2 | HRH2 | Human | Histamine | A | pKi | 6.08 | 6.08 | 6.08 | ChEMBL |
5-HT7 | 5HT7R | Human | 5-Hydroxytryptamine | A | pKi | 5.56 | 5.56 | 5.56 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 5.89 | 5.89 | 5.89 | ChEMBL |
α2A | ADA2A | Human | Adrenoceptors | A | pKi | 5.47 | 5.47 | 5.47 | ChEMBL |
5-HT2B | 5HT2B | Human | 5-Hydroxytryptamine | A | pKi | 6.64 | 6.64 | 6.64 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 5.77 | 5.77 | 5.77 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |