CHEMBL425983


SMILES Cc1nc2ccccc2c(Nc2ccc(N3CCN4CCCCC4C3)cc2)c1C
InChIKey MZAWJNSMQVUPQW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.88 5.88 5.88 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 8.64 8.64 8.64 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.15 6.15 6.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database