SULFISOXAZOLE
| SMILES | Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C |
| InChIKey | NHUHCSRWZMLRLA-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 3 |
| Molecular weight (Da) | 267.1 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| ETA | EDNRA | Human | Endothelin | A | pKi | 4.87 | 4.87 | 4.87 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| ETA | EDNRA | Rat | Endothelin | A | pIC50 | 5.05 | 5.75 | 6.11 | ChEMBL |
| ETB | EDNRB | Human | Endothelin | A | pIC50 | 4.62 | 4.62 | 4.62 | ChEMBL |
| ETA | EDNRA | Human | Endothelin | A | pIC50 | 4.66 | 5.74 | 6.11 | ChEMBL |
| TSH | TSHR | Human | Glycoprotein hormone | A | Potency | 4.9 | 5.8 | 6.4 | ChEMBL |
| H4 | HRH4 | Human | Histamine | A | pIC50 | 8.26 | 8.26 | 8.26 | Drug Central |
| ETA | EDNRA | Human | Endothelin | A | pIC50 | 8.21 | 8.21 | 8.21 | Drug Central |
| ETB | EDNRB | Human | Endothelin | A | pIC50 | 8.34 | 8.34 | 8.34 | Drug Central |
| ETA | EDNRA | Rat | Endothelin | A | pIC50 | 8.21 | 8.21 | 8.21 | Drug Central |