CHEMBL4544504


SMILES CC(C)c1[nH]c2nc(N)nn2c(=O)c1Cc1ccc(Cl)c(Br)c1
InChIKey WKTVEPAXEKXDKZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 395.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR2 CCR2 Human Chemokine A pKi 9.4 9.41 9.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR2 CCR2 Human Chemokine A pEC50 6.83 7.42 7.91 ChEMBL
CCR2 CCR2 Human Chemokine A pIC50 8.4 8.4 8.4 ChEMBL
CCR5 CCR5 Human Chemokine A pEC50 8.05 8.19 8.3 ChEMBL
CCR5 CCR5 Human Chemokine A pIC50 6.95 6.95 6.95 ChEMBL