CHEMBL4294246


SMILES CNc1ncc(C(=O)NC(c2ccccc2)c2ccccc2)c2nc(-c3ccco3)nn12
InChIKey UHDZPXOSQNQCSS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2B AA2BR Human Adenosine A pKi 5.0 5.0 5.0 ChEMBL
A3 AA3R Human Adenosine A pKi 8.29 8.29 8.29 ChEMBL
A2A AA2AR Human Adenosine A pKi 7.21 7.21 7.21 ChEMBL
A1 AA1R Human Adenosine A pKi 7.55 7.55 7.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database