CHEMBL1257810
SMILES | O=C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cc2ccc1CCc1ccc(cc1)CC2 |
InChIKey | SBJOJKQLHNFZTE-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 1 |
Rotatable bonds | 6 |
Molecular weight (Da) | 487.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D1 | DRD1 | Pig | Dopamine | A | pKi | 5.01 | 5.01 | 5.01 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 7.41 | 7.41 | 7.41 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 7.77 | 7.77 | 7.77 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 7.68 | 7.79 | 7.89 | ChEMBL |
5-HT2A | 5HT2A | Pig | 5-Hydroxytryptamine | A | pKi | 5.62 | 5.62 | 5.62 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |