CHEMBL438432


SMILES CCN(CC)CC(c1ccccc1F)N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)CC2(C)NCc3ccccc32)CC1
InChIKey XEJWRNRUPWQYOB-AIZFUAJFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight (Da) 633.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 4.7 4.7 4.7 ChEMBL
MC5 MC5R Human Melanocortin A pKi 5.85 5.85 5.85 ChEMBL
MC3 MC3R Human Melanocortin A pKi 4.8 4.8 4.8 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.13 7.13 7.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database