CHEMBL4595149


SMILES CN(CCCSc1nnc(-c2ccccc2)n1C)CC1CC1c1cc(F)ccc1OCCF
InChIKey NYXISGQCRCGPPX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 12
Molecular weight (Da) 472.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.67 5.67 5.67 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.83 5.83 5.83 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.01 6.01 6.01 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.25 6.25 6.25 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.61 5.61 5.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database