CHEMBL4595245


SMILES CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)NCCCCC1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc32)CC1
InChIKey KTMWGHBDOVXVOW-PXLJZGITSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 6
Rotatable bonds 17
Molecular weight (Da) 739.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.15 6.15 6.15 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.53 6.53 6.53 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.0 5.0 5.0 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.33 7.33 7.33 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.06 7.06 7.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database