CHEMBL442014


SMILES CN(CCCCCCCCN(C)CCCCCCNCC(=O)N1c2ccccc2C(=O)Nc2cccnc21)CCCCCCNCC(=O)N1c2ccccc2C(=O)Nc2cccnc21
InChIKey QBIRETGBCIAZCS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 4
Rotatable bonds 27
Molecular weight (Da) 872.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 6.76 6.76 6.76 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 8.62 8.62 8.62 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 8.77 8.77 8.77 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 9.14 9.14 9.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database