CHEMBL459350


SMILES CN(CCC=C1c2ccccc2CCc2ccccc21)Cc1ccc(OCCCN2CCCCC2)cc1
InChIKey TZZKWSLLNPOOCC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 494.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 6.56 6.56 6.56 ChEMBL
H1 HRH1 Human Histamine A pKi 7.1 7.1 7.1 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.52 6.52 6.52 ChEMBL
H3 HRH3 Human Histamine A pKi 9.5 9.55 9.6 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.17 7.17 7.17 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.0 7.0 7.0 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.52 6.52 6.52 PDSP Ki database
H1 HRH1 Human Histamine A pKi 7.1 7.1 7.1 PDSP Ki database
H3 HRH3 Human Histamine A pKi 9.6 9.6 9.6 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.0 7.0 7.0 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 7.17 7.17 7.17 PDSP Ki database
D5 DRD5 Human Dopamine A pKi 6.56 6.56 6.56 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database