CHEMBL442815


SMILES CO/N=C/c1ccccc1OC(C)C1=NCCN1
InChIKey YTQHOBJMFUQZEK-CXUHLZMHSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 247.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.92 5.92 5.92 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.51 5.51 5.51 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.18 6.18 6.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 6.3 6.3 6.3 ChEMBL