CHEMBL4595125


SMILES CC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCCC1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc32)CC1
InChIKey ZPMRLGPLMNVIDC-PXLJZGITSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 6
Rotatable bonds 17
Molecular weight (Da) 739.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.13 7.13 7.13 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.97 7.97 7.97 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.74 8.74 8.74 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.52 7.52 7.52 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.79 5.79 5.79 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database