CHEMBL4595409
SMILES | CCOc1ccc(F)cc1C1CC1CNCCCSc1nnc(-c2ccccc2)n1C |
InChIKey | AARWZLCCVAYIQN-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 6 |
Hydrogen bond donors | 1 |
Rotatable bonds | 11 |
Molecular weight (Da) | 440.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D5 | DRD5 | Human | Dopamine | A | pKi | 6.23 | 6.23 | 6.23 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 6.3 | 6.3 | 6.3 | ChEMBL |
D1 | DRD1 | Human | Dopamine | A | pKi | 6.53 | 6.53 | 6.53 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.66 | 6.66 | 6.66 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.18 | 6.18 | 6.18 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |