CHEMBL4435641


SMILES O=C(OCCCc1ccc(Cl)c(Cl)c1)N(c1ccccc1)C1CN2CCC1CC2
InChIKey JGOLLLMMDGFRBE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 432.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.89 6.89 6.89 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.22 7.22 7.22 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.52 6.52 6.52 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.77 6.77 6.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database