CHEMBL1258344


SMILES O=C1NC(=O)C(c2ccccc2)(c2ccccc2)N1CC(O)CN1CCN(c2ccccc2)CC1
InChIKey ROSFUYQZCZTAGG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 470.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 5.84 5.84 5.84 ChEMBL
α1B ADA1B Human Adrenoceptors A pKd 6.34 6.34 6.34 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 5.98 5.98 5.98 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.13 6.13 6.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database