CHEMBL4597188
SMILES | CCCN(CCCCNC(=O)c1ccc2ccccc2c1)C[C@H]1C[C@@H]1c1cccc(Cl)c1Cl |
InChIKey | KFWJKLDOLDILRK-NOZRDPDXSA-N |
Chemical properties
Hydrogen bond acceptors | 2 |
Hydrogen bond donors | 1 |
Rotatable bonds | 11 |
Molecular weight (Da) | 482.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D4 | DRD4 | Human | Dopamine | A | pKi | 6.11 | 6.11 | 6.11 | ChEMBL |
D1 | DRD1 | Human | Dopamine | A | pKi | 5.98 | 5.98 | 5.98 | ChEMBL |
5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pKi | 6.86 | 6.86 | 6.86 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 7.68 | 7.68 | 7.68 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 5.94 | 5.94 | 5.94 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pEC50 | 5.45 | 5.45 | 5.45 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pEC50 | 7.0 | 7.0 | 7.0 | ChEMBL |