CHEMBL4636148


SMILES CN1CCc2cccc3c2C1Cc1ccc(NC(N)=O)cc1-3
InChIKey YBSSDSCEOFCFIV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 293.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.35 8.35 8.35 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.31 7.31 7.31 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.61 5.61 5.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.9 6.9 6.9 ChEMBL