CHEMBL4636528


SMILES O=C(Nc1ccc(F)cc1-c1ccc(F)c(Cl)c1)OCC1CCNCC1
InChIKey GUWDPEQJYFKDCE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 380.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 10.16 10.16 10.16 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.47 8.47 8.47 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 9.57 9.57 9.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pEC50 8.03 8.27 8.39 ChEMBL