CHEMBL1172754


SMILES FC(F)(F)c1ccc(N2CCC(Cc3c[nH]cn3)CC2)cc1
InChIKey UUTLATQGKXUVDD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 309.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.67 6.67 6.67 ChEMBL
H3 HRH3 Human Histamine A pKi 8.74 8.74 8.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pEC50 8.96 8.96 8.96 ChEMBL